TIN: AN R PACKAGE FOR TRANSCRIPTOME INSTABILITY ANALYSIS

TIN: An R Package for Transcriptome Instability Analysis

Alternative splicing is a key regulatory mechanism for gene expression, vital for the proper functioning of eukaryotic cells.Disruption of normal pre-mRNA splicing has the potential to cause and reinforce human disease.Owing to rapid advances in high-throughput technologies, it is now possible to identify novel mRNA isoforms and detect aberrant spl

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Transcending the Technocratic Mentality through the Humanities

Catholic education has a long tradition of engagement with the liberal arts and especially the humanities.The place of the humanities today in the curriculum is under threat for several reasons, one being the predominance Spin Bike Pedals of the technocratic mentality.This paper revisits (in three steps) the contested issue of the role of the human

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FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1

Abstract Colorectal cancer (CRC) ranks as the second most lethal cancer worldwide because of its high rate of metastasis, and approximately 20% of CRC patients have metastases at initial diagnosis.Metabolic reprogramming, a hallmark of cancer cells, has been implicated in the process of metastasis.We previously demonstrated that fucosyltransferase

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